Antibody-Binding Proteins and Conjugates
Jackson Immuno Research Labs Rhodamine (TRITC)-IgG Fraction Monoclonal Mouse Anti-Biotin
Rhodamine (TRITC)-IgG Fraction Monoclonal Mouse Anti-Biotin
Cayman Chemical CefamndolesodIum salt 500mg
A cephalosporin antibiotic that is effective against E. coli (MIC values range from 0.25-2 mg/L depending on strain) as well as H. influenza and S. aureus
Cayman Chemical BromfenacsodIum salt 50mg
A COX-2 inhibitor (IC50 = 6.6 nM); selective over COX-1 (IC50 = 210 nM); inhibits PGE2 production in a rabbit model of LPS-induced eye inflammation; decreases inflammation following cataract removal in dogs (0.9% topically on a tapering schedule for 24 weeks)
Carbosynth LLC. Streptavidin protein (HRP), 1 mg
Purified homogeneous preparation of HRP conjugated Streptavidin protein
Biotium Insulin(2D11-H5), CF488A conjugate, 0.1mg/mL
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
Cayman Chemical NCS-382sodIum salt 50mg
A GHBR antagonist (IC50s = 134.1 and 201.3 nM in isolated rat striatal and hippocampal membranes, respectively, in radioligand binding assays); selective for GHBR over GABA binding sites in rat brain synaptic membranes at 1 and 10 µM; decreases GHB-induced increases in inositol phosphate accumulation and cGMP levels in isolated rat hippocampal slices (IC50s = 8.6 and 30 µM, respectively); reduces GHB-induced increases in the time mice spent immobile in the forced swim test at 1.66 and 2.08 mmol/kg; decreases spike and wave discharges in audiogenic seizure-susceptible Swiss Rb mice, as well as a rat model of petit mal epilepsy, at 2.3 mmol/kg
Biotium Fibronectin(2755-8), CF488A conjugate, 0.1mg/mL
Fibronectin is an extracellular matrix glycoprotein present on most cell surfaces, in extracellular fluids and in plasma. A high molecular weight heterodimeric protein, it was originally discovered as a protein missing from the surfaces of virus-transformed cells, and it has been shown to be involved in various functions including cell adhesion, cell motility and wound healing. Alternative splicing and glycosylation give rise to several different forms of Fibronectin, some of which exhibit restricted tissue distribution or association with malignancies. It has been shown that Myofibroblasts phenotype formation correlates with the occurrence of glycosylated Fibronectin and Fibronectin splice variants in Dupuytren's disease.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for det
Cayman Chemical MezlocIlInsodIum salt 500mg
A β-lactam antibiotic; active against B. fragilis, E. lentum, P. morbillorum, and F. nucleatum (MICs = 8, 4, 2, and 4 UG/ml, respectively); active against 10 strains of S. faecalis at 32 UG/ml; increases survival and reduces bacteremia in a rabbit model of S. faecalis endocarditis; completely eliminates lung P. morbillorum, E. lentum, and F. nucelatum, but not B. fragilis, in a rabbit model of pulmonary P. morbillorum, E. lentum, F. nucelatum, and B. fragilis infection at 300 mg/kg
Fluidigm Corp ANTI-MOUSE CD45R/B220 -176YB
CD45R, also known as B220, is the longest isoform of CD45, with a glycosylation pattern resulting in a molecular weight of 220 kDa. B cells at all developmental stages express CD45R, as do subsets of T, NK, and dendritic cells. In mice, CD45R has been historically used as a pan-B cell marker. However, CD19 offers greater specificity for the B cell lineage.
Biotium CD282 / TLR2(TLR2/221), CF594 conjugate, 0.1mg/mL
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
Cayman Chemical ClavulnatepotasIum salt 50mg
A β-lactamase inhibitor that is effective against Ambler class A β-lactamases (IC50 values range from 12 to 60 nM); commonly used with other antibiotics that would be inactivated by β-lactamases
Biotium Thyroglobulin(2H11), CF488A conjugate, 0.1mg/mL
MAb 2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined
